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Molecular Depot High HAMA Serum and Plasma Matched Set S2010006P
High HAMA Serum and Plasma Matched Set is a matched set of Serum and K3 EDTA Plasma samples (1 mL each), with their anti-mouse antibodies (HAMA) titer established with a cleared HAMA ELISA method. This set is to be used to test HAMA interference in immunoassays.
High HAMA Serum and Plasma Matched Set
| Catalog number: | S2010006P |
| Lot number: | Batch Dependent |
| Expiration date: | Batch Dependent |
| Volume: | 2 x 1 mL (1 mL serum and 1 mL K3 EDTA Plasma) |
| Appearance: | Yellow orange |
| Matrix: | Human serum and plasma |
| Storage: | At -20°C or lower. Avoid repeated freeze-thaw cycles. Aliquot as needed. |
| Keywords | HAMA sample, Human Anti-Mouse Antibodies serum, High HAMA plasma |
About HAMA
Immunoassays rely heavily on mouse antibodies for the detection of various analytes. The accuracy of these assays can, however, suffer when samples contain human anti-mouse antibodies (HAMA). Indeed, HAMA are often associated with inaccurate results because they can bind to both capture and detection antibodies and can generate non-specific signals. This so-called HAMA effect is major interference issue. Assessing the tolerance of an immunoassay to HAMA and mitigating it is very important important during research and development.
Products Related to High HAMA Serum and Plasma Matched Set: High HAMA Serum
References:
1: Mukherjee S, Ayanambakkam A, Ibrahimi S, Schmidt S, Charkrabarty JH, Khawandanah M. Ibritumomab tiuxetan (Zevalin) and elevated serum human anti-murine antibody (HAMA) Hematol Oncol Stem Cell Ther. 2018 Sep;11(3):187-188.
2: Klee GG. Human anti-mouse antibodies Arch Pathol Lab Med. 2000 Jun;124(6):921-3.
3: Wang G, An Y, Zhang X, Ding P, Bi H, Zhao Z. Chondrocyte Spheroids Laden in GelMA/HAMA Hybrid Hydrogel for Tissue-Engineered Cartilage with Enhanced Proliferation, Better Phenotype Maintenance, and Natural Morphological Structure Gels. 2021 Dec 2;7(4):247.
4: Mouser VH, Abbadessa A, Levato R, Hennink WE, Vermonden T, Gawlitta D, Malda J. Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs Biofabrication. 2017 Mar 23;9(1):015026.
5: Maier W, Buller R, Philipp M, Heuser I. The Hamilton Anxiety Scale: reliability, validity and sensitivity to change in anxiety and depressive disorders J Affect Disord. 1988 Jan-Feb;14(1):61-8.
6: Imasaka KI, Tomita Y. Reply Ann Thorac Surg. 2018 Oct;106(4):1264-1265.
7: Imasaka KI, Tomita Y. Reply Ann Thorac Surg. 2018 Oct;106(4):1258-1259.
8: Xia C, Chen P, Mei S, Ning L, Lei C, Wang J, Zhang J, Ma J, Fan S. Photo-crosslinked HAMA hydrogel with cordycepin encapsulated chitosan microspheres for osteoarthritis treatment Oncotarget. 2017 Jan 10;8(2):2835-2849.
9: Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Schläfke S, Dienel A. Lavender oil preparation Silexan is effective in generalized anxiety disorder–a randomized, double-blind comparison to placebo and paroxetine Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69.
10: Matza LS, Morlock R, Sexton C, Malley K, Feltner D. Identifying HAM-A cutoffs for mild, moderate, and severe generalized anxiety disorder Int J Methods Psychiatr Res. 2010 Dec;19(4):223-32.
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- Customer name and address
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Important Information
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Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
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