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Molecular Depot KYT-1 (Highly Pure) MDP0901
KYT-1 (Highly Pure) is a synthetic molecular of 619.76 g/mol. Its IUPAS name is (3S)-N-[(1S)-5-Amino-1-(N,N-dimethylcarbamoyl)pentyl]-3-[(2S)-6-amino-2-(benzyloxycarbonyl)aminohexanoylamino]-6-guanidino-2-oxohexanamide(Hydrochloride Form). This product is for in vitro research use only. This product is not for human or animal use. Custom bulk amounts of this product are available upon request.
References
1: Nakagawa Y, Nishikimi T, Kuwahara K. Atrial and brain natriuretic peptides: Hormones secreted from the heart Peptides. 2019 Jan;111:18-25.
2: Rubattu S, Gallo G. The Natriuretic Peptides for Hypertension Treatment High Blood Press Cardiovasc Prev. 2022 Jan;29(1):15-21.
3: Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, Liu S, Tan J, Yan Q. ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats Cell Death Dis. 2017 Oct 26;8(10):e3145.
4: Theilig F, Wu Q. ANP-induced signaling cascade and its implications in renal pathophysiology Am J Physiol Renal Physiol. 2015 May 15;308(10):F1047-55.
5: Chen C, Zhang Y, Tao M, Zhao X, Feng Q, Fei X, Fu Y. Atrial Natriuretic Peptide Attenuates Colitis via Inhibition of the cGAS-STING Pathway in Colonic Epithelial Cells Int J Biol Sci. 2022 Feb 7;18(4):1737-1754.
6: Hirsch JR, Meyer M, Forssmann WG. ANP and urodilatin: who is who in the kidney Eur J Med Res. 2006 Oct 27;11(10):447-54.
7: Sugawara A, Nakao K, Morii N, Yamada T, Itoh H, Shiono S, Saito Y, Mukoyama M, Arai H, Nishimura K, et al. Synthesis of atrial natriuretic polypeptide in human failing hearts. Evidence for altered processing of atrial natriuretic polypeptide precursor and augmented synthesis of beta-human ANP J Clin Invest. 1988 Jun;81(6):1962-70.
8: Itoh H, Nakao K, Sugawara A, Saito Y, Mukoyama M, Morii N, Yamada T, Shiono S, Arai H, Hosoda K, et al. Gamma-atrial natriuretic polypeptide (gamma ANP)-derived peptides in human plasma: cosecretion of N-terminal gamma ANP fragment and alpha ANP J Clin Endocrinol Metab. 1988 Sep;67(3):429-37.
9: Matsuo A, Nagai-Okatani C, Nishigori M, Kangawa K, Minamino N. Natriuretic peptides in human heart: Novel insight into their molecular forms, functions, and diagnostic use Peptides. 2019 Jan;111:3-17.
10: Therrien JP, Kim SM, Terunuma A, Qin Y, Tock CL, Pfützner W, Ohyama M, Schnermann J, Vogel JC. A gene therapy approach for long-term normalization of blood pressure in hypertensive mice by ANP-secreting human skin grafts Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1178-83.
Catalog number: MDP9901
Solubility: 1 mM in DMSO
IUPAC Name: (3S)-N-[(1S)-5-Amino-1-(N,N-dimethylcarbamoyl)pentyl]-3-[(2S)-6-amino-2-(benzyloxycarbonyl)aminohexanoylamino]-6-guanidino-2-oxohexanamide(Hydrochloride Form)
Amount: 1 mg
Molecular Weight: 619.76 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.
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