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Thumbnail Filmstrip of Molecular Depot 41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine) B2014861 Images
Molecular Depot 41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine) B2014861
41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine) is a high quality 41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine). This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine)
Catalog number:B2014861
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:50 ug
Molecular Weight or Concentration:N/A
Supplied as:Lyophilized
Applications:molecular tool for various biochemical applications
Storage:2-8°C
Keywords:41-Syn / Alpha-Synuclein (1-41) (Rat, Mouse, Porcine)
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Vinnakota RL, Yedlapudi D, Manda KM, Bhamidipati K, Bommakanti KT, RangaLakshmi GS, Kalivendi SV. Identification of an Alternatively Spliced α-Synuclein Isoform That Generates a 41-Amino Acid N-Terminal Truncated Peptide, 41-syn: Role in Dopamine Homeostasis ACS Chem Neurosci. 2018 Dec 19;9(12):2948-2958.
2: Lashuel HA, Overk CR, Oueslati A, Masliah E. The many faces of α-synuclein: from structure and toxicity to therapeutic target Nat Rev Neurosci. 2013 Jan;14(1):38-48.
3: Shahnawaz M, Mukherjee A, Pritzkow S, Mendez N, Rabadia P, Liu X, Hu B, Schmeichel A, Singer W, Wu G, Tsai AL, Shirani H, Nilsson KPR, Low PA, Soto C. Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy Nature. 2020 Feb;578(7794):273-277.
4: Ghosh D, Mehra S, Sahay S, Singh PK, Maji SK. α-synuclein aggregation and its modulation Int J Biol Macromol. 2017 Jul;100:37-54.
5: Dehay B, Bourdenx M, Gorry P, Przedborski S, Vila M, Hunot S, Singleton A, Olanow CW, Merchant KM, Bezard E, Petsko GA, Meissner WG. Targeting α-synuclein for treatment of Parkinson’s disease: mechanistic and therapeutic considerations Lancet Neurol. 2015 Aug;14(8):855-866.
6: Praschberger R, Kuenen S, Schoovaerts N, Kaempf N, Singh J, Janssens J, Swerts J, Nachman E, Calatayud C, Aerts S, Poovathingal S, Verstreken P. Neuronal identity defines α-synuclein and tau toxicity Neuron. 2023 May 17;111(10):1577-1590.e11.
7: Burmann BM, Gerez JA, Matečko-Burmann I, Campioni S, Kumari P, Ghosh D, Mazur A, Aspholm EE, Šulskis D, Wawrzyniuk M, Bock T, Schmidt A, Rüdiger SGD, Riek R, Hiller S. Regulation of α-synuclein by chaperones in mammalian cells Nature. 2020 Jan;577(7788):127-132.
8: Marino G, Calabresi P, Ghiglieri V. Alpha-synuclein and cortico-striatal plasticity in animal models of Parkinson disease Handb Clin Neurol. 2022;184:153-166.
9: Guiney SJ, Adlard PA, Lei P, Mawal CH, Bush AI, Finkelstein DI, Ayton S. Fibrillar α-synuclein toxicity depends on functional lysosomes J Biol Chem. 2020 Dec 18;295(51):17497-17513.
10: Siegert A, Rankovic M, Favretto F, Ukmar-Godec T, Strohäker T, Becker S, Zweckstetter M. Interplay between tau and α-synuclein liquid-liquid phase separation Protein Sci. 2021 Jul;30(7):1326-1336.
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