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Molecular Depot Histone H4 Peptide Substrate B2013001
Histone H4 Peptide Substrate is a high quality peptide containing a lysine at position 20 and is substrate for lysine methyltransferases. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Histone H4 Peptide Substrate
Catalog number:B2013001
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:1 mg
Molecular Weight or Concentration:1278.0 g/mol
Supplied as:Lyophilized Powder
Applications:molecular tool for various biochemical applications
Storage:-20°C
Keywords:Histone H4K20 Peptide, SET8 Methyltransferase Acceptor Peptide
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Peptide microarrays to interrogate the “histone code” Methods Enzymol. 2012;512:107-35.
2: Bab I, Smith E, Gavish H, Attar-Namdar M, Chorev M, Chen YC, Muhlrad A, Birnbaum MJ, Stein G, Frenkel B. Biosynthesis of osteogenic growth peptide via alternative translational initiation at AUG85 of histone H4 mRNA J Biol Chem. 1999 May 14;274(20):14474-81.
3: Nozaki T, Kanai M. Chemical Catalysis Intervening to Histone Epigenetics Acc Chem Res. 2021 May 4;54(9):2313-2322.
4: Mann SA, DeMart MK, May B, Causey CP, Knuckley B. Histone H4-based peptoids are inhibitors of protein arginine methyltransferase 1 (PRMT1) Biochem J. 2020 Aug 28;477(16):2971-2980.
5: Makowski AM, Dutnall RN, Annunziato AT. Effects of acetylation of histone H4 at lysines 8 and 16 on activity of the Hat1 histone acetyltransferase J Biol Chem. 2001 Nov 23;276(47):43499-502.
6: Moreno-Yruela C, Bæk M, Vrsanova AE, Schulte C, Maric HM, Olsen CA. Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases Nat Commun. 2021 Jan 4;12(1):62.
7: Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors PLoS One. 2014 Feb 28;9(2):e90095.
8: Camporeale G, Shubert EE, Sarath G, Cerny R, Zempleni J. K8 and K12 are biotinylated in human histone H4 Eur J Biochem. 2004 Jun;271(11):2257-63.
9: Liu J , Tang Y , Yang W , Tao B , He Y , Shen X , Shen T , Lin C , Cai K . Functionalization of titanium substrate with multifunctional peptide OGP-NAC for the regulation of osteoimmunology Biomater Sci. 2019 Mar 26;7(4):1463-1476.
10: Kinney CM, Chandrasekharan UM, Yang L, Shen J, Kinter M, McDermott MS, DiCorleto PE. Histone H3 as a novel substrate for MAP kinase phosphatase-1 Am J Physiol Cell Physiol. 2009 Feb;296(2):C242-9.
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- Reason for return
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Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
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