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Molecular Depot Jacaric Acid Methyl Ester B2012828
Jacaric Acid Methyl Ester is a high quality methyl ester form of the conjugated PUFA jacaric acid. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Jacaric Acid Methyl Ester
Catalog number:B2012828
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:1 mg
Molecular Weight or Concentration:292.5 g/mol
Supplied as:Solution
Applications:molecular tool for various biochemical applications
Storage:-20°C
Keywords:Methyl jacarate, Methyl 8(Z),10(E),12(Z)-Octadecatrienoate
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Gasmi J, Thomas Sanderson J. Jacaric acid and its octadecatrienoic acid geoisomers induce apoptosis selectively in cancerous human prostate cells: a mechanistic and 3-D structure-activity study Phytomedicine. 2013 Jun 15;20(8-9):734-42.
2: Liu WN, Leung KN. Jacaric acid inhibits the growth of murine macrophage-like leukemia PU5-1.8 cells by inducing cell cycle arrest and apoptosis Cancer Cell Int. 2015 Sep 29;15:90.
3: Liu WN, Leung KN. The Immunomodulatory Activity of Jacaric Acid, a Conjugated Linolenic Acid Isomer, on Murine Peritoneal Macrophages PLoS One. 2015 Dec 2;10(12):e0143684.
4: Shinohara N, Ito J, Tsuduki T, Honma T, Kijima R, Sugawara S, Arai T, Yamasaki M, Ikezaki A, Yokoyama M, Nishiyama K, Nakagawa K, Miyazawa T, Ikeda I. jacaric acid, a linolenic acid isomer with a conjugated triene system, reduces stearoyl-CoA desaturase expression in liver of mice J Oleo Sci. 2012;61(8):433-41.
5: Kijima R, Honma T, Ito J, Yamasaki M, Ikezaki A, Motonaga C, Nishiyama K, Tsuduki T. Jacaric acid is rapidly metabolized to conjugated linoleic acid in rats J Oleo Sci. 2013;62(5):305-12.
6: Liu WN, Leung KN. Apoptosis- and differentiation-inducing activities of jacaric acid, a conjugated linolenic acid isomer, on human eosinophilic leukemia EoL-1 cells Oncol Rep. 2014 Nov;32(5):1881-8.
7: Liu WN, Leung KN. Anti-allergic effect of the naturally-occurring conjugated linolenic acid isomer, jacaric acid, on the activated human mast cell line-1 Biomed Rep. 2015 Nov;3(6):839-842.
8: Shinohara N, Tsuduki T, Ito J, Honma T, Kijima R, Sugawara S, Arai T, Yamasaki M, Ikezaki A, Yokoyama M, Nishiyama K, Nakagawa K, Miyazawa T, Ikeda I. Jacaric acid, a linolenic acid isomer with a conjugated triene system, has a strong antitumor effect in vitro and in vivo Biochim Biophys Acta. 2012 Jul;1821(7):980-8.
9: Dhar Dubey KK, Sharma G, Kumar A. Conjugated Linolenic Acids: Implication in Cancer J Agric Food Chem. 2019 Jun 5;67(22):6091-6101.
10: Van Nieuwenhove CP, Del Huerto Moyano A, Van Nieuwenhove GA, Molina V, Luna Pizarro P. Jacaranda oil administration improves serum biomarkers and bioavailability of bioactive conjugated fatty acids, and alters fatty acid profile of mice tissues Lipids. 2022 Jan;57(1):33-44.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
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- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
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Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
All exchanges and returns require the completion of a Return Merchandise Authorization (RMA) form. Once completed, please return the merchandise immediately as the RMA number is only active for ten (10) days from the date of issuance.
Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
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