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Molecular Depot Collagenase Substrate (Highly Pure) B2012711
Collagenase Substrate (Highly Pure) is a high quality substrate for quantitative collagenase determination. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Collagenase Substrate (Highly Pure)
Catalog number:B2012711
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:25 mg
Molecular Weight or Concentration:588.6 g/mol
Supplied as:Lyophilized Powder
Applications:molecular tool for various biochemical applications
Storage:-20°C
Keywords:Z-Gly-Pro-Gly-Gly-Pro-Ala-OH
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: De Souza SJ, Pereira HM, Jacchieri S, Brentani RR. Collagen/collagenase interaction: does the enzyme mimic the conformation of its own substrate? FASEB J. 1996 Jun;10(8):927-30.
2: Ikeuchi T, Yasumoto M, Takita T, Tanaka K, Kusubata M, Hayashida O, Hattori S, Mizutani K, Mikami B, Yasukawa K. Crystal structure of Grimontia hollisae collagenase_provides insights into its novel substrate specificity toward collagen J Biol Chem. 2022 Aug;298(8):102109.
3: Leber TM, Balkwill FR. Zymography: a single-step staining method for quantitation of proteolytic activity on substrate gels Anal Biochem. 1997 Jun 15;249(1):24-8.
4: Bhattacharya S, Bhattacharya S, Gachhui R, Hazra S, Mukherjee J. U32 collagenase_from Pseudoalteromonas agarivorans NW4327: Activity, structure, substrate interactions and molecular dynamics simulations Int J Biol Macromol. 2019 Mar 1;124:635-650.
5: Tsu CA, Craik CS. Substrate recognition by recombinant serine collagenase 1 from Uca pugilator J Biol Chem. 1996 May 10;271(19):11563-70.
6: Al-Abdullah IH, Bagramyan K, Bilbao S, Qi M, Kalkum M. Fluorogenic Peptide Substrate for Quantification of Bacterial Enzyme Activities Sci Rep. 2017 Mar 13;7:44321.
7: Deng SJ, Bickett DM, Mitchell JL, Lambert MH, Blackburn RK, Carter HL 3rd, Neugebauer J, Pahel G, Weiner MP, Moss ML. Substrate specificity of human collagenase_3 assessed using a phage-displayed peptide library J Biol Chem. 2000 Oct 6;275(40):31422-7.
8: Saikumari YK, Balaram P. An internally quenched fluorescent substrate for collagenase Biopolymers. 2008;90(2):131-7.
9: Shima H, Inagaki A, Imura T, Yamagata Y, Watanabe K, Igarashi K, Goto M, Murayama K. Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation J Diabetes Res. 2016;2016:4396756.
10: Hasty KA, Jeffrey JJ, Hibbs MS, Welgus HG. The collagen substrate specificity of human neutrophil collagenase J Biol Chem. 1987 Jul 25;262(21):10048-52.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
- Spectra Services shipping order number
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- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
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Spectra Services reserves the right to review this policy on a case-by-case basis.
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Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
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Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
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