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Molecular Depot Human CPEB1 Protein B2012017
Human CPEB1 Protein is a high quality recombinant human CPEB1 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Human CPEB1 Protein
Catalog number:B2012017
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:100 µg
Molecular Weight or Concentration:1 mg/mL
Supplied as:Solution
Applications:molecular tool for various biochemical applications
Storage:-20 °C
Keywords:Cytoplasmic polyadenylation element bindi ng protein 1 protein, CEBP protein, CPE-BP1 protein, CPEB protein
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Picó S, Parras A, Santos-Galindo M, Pose-Utrilla J, Castro M, Fraga E, Hernández IH, Elorza A, Anta H, Wang N, Martí-Sánchez L, Belloc E, Garcia-Esparcia P, Garrido JJ, Ferrer I, Macías-García D, Mir P, Artuch R, Pérez B, Hernández F, Navarro P, López-Sendón JL, Iglesias T, Yang XW, Méndez R, Lucas JJ. CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s disease Sci Transl Med. 2021 Sep 29;13(613):eabe7104.
2: Jin X, Gao J, Zheng R, Yu M, Ren Y, Yan T, Huang Y, Li Y. Antagonizing circRNA_002581-miR-122-CPEB1 axis alleviates NASH through restoring PTEN-AMPK-mTOR pathway regulated autophagy Cell Death Dis. 2020 Feb 13;11(2):123.
3: Batra R, Stark TJ, Clark E, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, Ares M Jr, Spector DH, Yeo GW. RNA-binding protein CPEB1 remodels host and viral RNA landscapes Nat Struct Mol Biol. 2016 Dec;23(12):1101-1110.
4: França MM, Mendonca BB. Genetics of ovarian insufficiency and defects of folliculogenesis Best Pract Res Clin Endocrinol Metab. 2022 Jan;36(1):101594.
5: Wang J, Wang T, Zhang Y, Liu J, Song J, Han Y, Wang L, Yang S, Zhu L, Geng R, Li W, Yu X. CPEB1 enhances erastin-induced ferroptosis in gastric cancer cells by suppressing twist1 expression IUBMB Life. 2021 Sep;73(9):1180-1190.
6: Xu M, Fang S, Song J, Chen M, Zhang Q, Weng Q, Fan X, Chen W, Wu X, Wu F, Tu J, Zhao Z, Ji J. CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance Cell Death Dis. 2018 Sep 20;9(10):957.
7: Hui X, Zhang S, Wang Y. miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma Mol Med Rep. 2018 Oct;18(4):3965-3972.
8: Sovijit W, Sovijit W, Ishii Y, Kambe J, Fujita T, Watanabe G, Yamaguchi H, Nagaoka K. Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression Biochem Biophys Res Commun. 2021 Jan 1;534:871-876.
9: Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, Richter JD. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis Oncogene. 2016 Jun 2;35(22):2893-901.
10: Jiao W, Zhao S, Liu R, Guo T, Qin Y. CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort J Ovarian Res. 2020 Apr 30;13(1):49.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
- Spectra Services shipping order number
- Date of invoice
- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
Non-Returnable Goods
Unfortunately, Spectra Services is unable to accept the following returns at this time:
- Products not in completely resalable condition (including products with damaged, missing, or defaced labeling or packaging
- Chemicals, reagents, diagnostics, sterile, or any controlled products (unless products do not meet specification
- Laboratory apparatus or instruments that have been used or are without the original packaging, labeling and operating manuals
- Refrigerated products or other perishables
- Products which are not inventoried by Spectra Services and are not able to be returned to the manufacturer
- Products purchased on a special order
- Products not purchased from Spectra Services
- Products with an expired shelf life or an expiration date too short for resale
- Discontinued products
Spectra Services reserves the right to review this policy on a case-by-case basis.
Pre-Owned Products
Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
All exchanges and returns require the completion of a Return Merchandise Authorization (RMA) form. Once completed, please return the merchandise immediately as the RMA number is only active for ten (10) days from the date of issuance.
Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
Spectra Services highly recommends that return packages be insured for full value and packaged securely to prevent shipping damage.
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249 David Parkway
Ontario, NY 14519 US
Phone: 585-265-4320
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Accidental damage during shipment can sometimes happen. When you take delivery of your freight, please inspect thoroughly for any visible damage to the outside of the shipping container before signing for it. If there are multiple pieces to the shipment, please account for all them. Should you find that any of the products are damaged or missing after receipt, contact us within three days to address the matter.
I'd like to make a return. How do I do that?
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