Molecular Depot Mouse ACY1 Protein B2011286
Mouse ACY1 Protein is a high quality zinc-binding enzyme that hydrolyses acylated L-amino acids. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Mouse ACY1 Protein
Catalog number:B2011286
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:20 µg
Molecular Weight or Concentration:250 µg/mL
Supplied as:Solution
Applications:molecular tool for various biochemical applications
Storage:2-8 °C
Keywords:Mouse ACY1 protein, Recombinant ACY1 protein, Aminoacylase 1 protein, ACY-1 protein, Acy1 protein, ACY1_HUMAN protein, ACY1D protein, ACYLASE protein, Acylase I protein, Aminoacylase-1 protein, EC 3.5.1.14 protein, epididymis secretory protein Li 5 protein
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Kim JH, Shinde DN, Reijnders MRF, Hauser NS, Belmonte RL, Wilson GR, Bosch DGM, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CTRM, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BBA, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, Wieczorek D, Bramswig N, Laccone FA, Behunova J, Rehder H, Gordon CT, Rio M, Romana S, Tang S, El-Khechen D, Cho MT, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann APA, Stevens SJC, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LELM, Ahn EYE. De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome Am J Hum Genet. 2016 Sep 1;99(3):711-719.
2: Yu B, Liu X, Cao X, Zhang M, Chang H. Study of the expression and function of ACY1 in patients with colorectal cancer Oncol Lett. 2017 Apr;13(4):2459-2464.
3: Shi H, Hayes MT, Kirana C, Miller RJ, Keating JP, Stubbs RS. Overexpression of aminoacylase 1 is associated with colorectal cancer progression Hum Pathol. 2013 Jun;44(6):1089-97.
4: Sawazaki T, Minezawa M. The pig aminoacylase 1 (ACY1) and ribosomal protein L29 (RPL29)/heparin/heparan sulfate interacting protein (HIP) genes are located together at 13q21–>q22, corresponding to human 3p21.1 Cytogenet Cell Genet. 1999;86(1):56-61.
5: Lindner HA, Alary A, Wilke M, Sulea T. Probing the acyl-binding pocket of aminoacylase-1 Biochemistry. 2008 Apr 8;47(14):4266-75.
6: Cavalloni G, Peraldo-Neia C, Massa A, Bergamini C, Trentini A, De Rosa G, Daniele L, Ciccosanti F, Cervellati C, Leone F, Aglietta M. Proteomic analysis identifies deregulated metabolic and oxidative-associated proteins in Italian intrahepatic cholangiocarcinoma patients BMC Cancer. 2021 Jul 28;21(1):865.
7: Posavi M, Diaz-Ortiz M, Liu B, Swanson CR, Skrinak RT, Hernandez-Con P, Amado DA, Fullard M, Rick J, Siderowf A, Weintraub D, McCluskey L, Trojanowski JQ, Dewey RB Jr, Huang X, Chen-Plotkin AS. Characterization of Parkinson’s disease using blood-based biomarkers: A multicohort proteomic analysis PLoS Med. 2019 Oct 11;16(10):e1002931.
8: Wei X, Li J, Xie H, Ling Q, Wang J, Lu D, Zhou L, Xu X, Zheng S. Proteomics-based identification of the tumor suppressor role of aminoacylase 1 in hepatocellular carcinoma Cancer Lett. 2014 Aug 28;351(1):117-25.
9: Göverti D, Yüksel RN, Kaya H, Büyüklüoğlu N, Yücel Ç, Göka E. Serum concentrations of aminoacylase 1 in schizophrenia as a potential biomarker: a case-sibling-control study Nord J Psychiatry. 2022 Jul;76(5):380-385.
10: Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE. Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk JCI Insight. 2021 Mar 8;6(5):e144392.
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