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Molecular Depot Anti Human IgE Antibody (Epsilon Chain Specific) Conjugated to AP B2010787
Anti Human IgE Antibody (Epsilon Chain Specific) Conjugated to AP is a highly pure affinity-purified polyclonal antibody specific to human IgE Epsilon chains and conjugated to alkaline phosphatase. This product has been used as multipurpose antibody for various assay formats, including ELISA. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.
Anti Human IgE Antibody (Epsilon Chain Specific) Conjugated to AP
Catalog number:B2010787
Lot number:Batch Dependent
Expiration Date:Batch dependent
Amount:1 mg
Molecular Weight or Concentration:na
Supplied as:Lyophilized
Applications:multipurpose antibody for various assay formats, including ELISA
Storage:-20C
Keywords:anti-IgE AP, Epsilon specific anti-IgE AP, anti-IgE Epsilon AP, anti-IgE Epsilon Alkaline Phosphatase
Grade:Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: D’Amato G, Oldani V, Donner CF. Anti-IgE monoclonal antibody: a new approach to the treatment of allergic respiratory diseases Monaldi Arch Chest Dis. 2003 Jan-Mar;59(1):25-9.
2: Liu P, Pan Z, Gu C, Cao X, Liu X, Zhang J, Xiao Z, Wang X, Guo H, Ju D, Deng SJ. An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases Front Immunol. 2020 Nov 27;11:596908.
3: Jabs F, Plum M, Laursen NS, Jensen RK, Mølgaard B, Miehe M, Mandolesi M, Rauber MM, Pfützner W, Jakob T, Möbs C, Andersen GR, Spillner E. Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction Nat Commun. 2018 Jan 2;9(1):7.
4: Deniz YM, Gupta N. Safety and tolerability of omalizumab (Xolair), a recombinant humanized monoclonal anti-IgE antibody Clin Rev Allergy Immunol. 2005 Aug;29(1):31-48.
5: Johansson SG, Oman H, Nopp A, Pettersson S. The importance of IgE antibody levels in anti-IgE treatment Allergy. 2006 Oct;61(10):1216-9.
6: Qian W, Zhang X, Li B, Zhang D, Tong Q, Chen L, Zheng L, Kou G, Wang H, Hou S, Guo Y. Development and characterization of a novel anti-IgE monoclonal antibody Biochem Biophys Res Commun. 2010 May 14;395(4):547-52.
7: Fried AJ, Oettgen HC. Anti-IgE in the treatment of allergic disorders in pediatrics Curr Opin Pediatr. 2010 Dec;22(6):758-64.
8: Chu SY, Horton HM, Pong E, Leung IW, Chen H, Nguyen DH, Bautista C, Muchhal US, Bernett MJ, Moore GL, Szymkowski DE, Desjarlais JR. Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody J Allergy Clin Immunol. 2012 Apr;129(4):1102-15.
9: Kopp MV. Omalizumab: Anti-IgE therapy in allergy Curr Allergy Asthma Rep. 2011 Apr;11(2):101-6.
10: Pelst MP, Maina E, Vandenabeele S, Hesta M, Cox E. Detection of allergen-specific antibody-secreting cells in dogs by ELISPOT Vet Immunol Immunopathol. 2020 Oct;228:110101.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
- Spectra Services shipping order number
- Date of invoice
- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
Non-Returnable Goods
Unfortunately, Spectra Services is unable to accept the following returns at this time:
- Products not in completely resalable condition (including products with damaged, missing, or defaced labeling or packaging
- Chemicals, reagents, diagnostics, sterile, or any controlled products (unless products do not meet specification
- Laboratory apparatus or instruments that have been used or are without the original packaging, labeling and operating manuals
- Refrigerated products or other perishables
- Products which are not inventoried by Spectra Services and are not able to be returned to the manufacturer
- Products purchased on a special order
- Products not purchased from Spectra Services
- Products with an expired shelf life or an expiration date too short for resale
- Discontinued products
Spectra Services reserves the right to review this policy on a case-by-case basis.
Pre-Owned Products
Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
All exchanges and returns require the completion of a Return Merchandise Authorization (RMA) form. Once completed, please return the merchandise immediately as the RMA number is only active for ten (10) days from the date of issuance.
Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
Spectra Services highly recommends that return packages be insured for full value and packaged securely to prevent shipping damage.
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249 David Parkway
Ontario, NY 14519 US
Phone: 585-265-4320
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