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Molecular Depot Endostatin (Human, Recombinant) B2010299
Endostatin (Human, Recombinant) is a high quality research product used as highly pure Endostatin (Human, Recombinant) expressed in P. pastoris. This protein acts as an endogenous antiangiogenic peptide with multiple antitumor roles that stem from the modulation of various receptors in the plasma membrane. Custom bulk orders of this product are available upon request.
Endostatin (Human, Recombinant)
Catalog number:B2010299
Lot number:Batch Dependent
Expiration Date:Batch dependent
Volume/Weight:10 ug
pH:7.4 upon reconstitution
Supplied as:Lyophilized Powder
Appearance:Powder
Applications:highly pure Endostatin (Human, Recombinant) expressed in P. pastoris. This protein acts as an endogenous antiangiogenic peptide with multiple antitumor roles that stem from the modulation of various receptors in the plasma membrane.
Storage:-20C
Keywords:rHuEndostatin; Collagen alpha-1(XV) chain
Grade:Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Walia A, Yang JF, Huang YH, Rosenblatt MI, Chang JH, Azar DT. Endostatin’s
emerging roles in angiogenesis, lymphangiogenesis, disease, and clinical
applications. Biochim Biophys Acta. 2015 Dec;1850(12):2422-38.
PMC4624607.
2: Fu Y, Tang H, Huang Y, Song N, Luo Y. Unraveling the mysteries of endostatin.
IUBMB Life. 2009 Jun;61(6):613-26.
3: Lamattina AM, Poli S, Kidambi P, Bagwe S, Courtwright A, Louis PH, Shrestha
S, Stump B, Goldberg HJ, Thiele EA, Rosas I, Henske EP, El-Chemaly S. Serum
endostatin levels are associated with diffusion capacity and with tuberous
sclerosis- associated lymphangioleiomyomatosis. Orphanet J Rare Dis. 2019 Mar
29;14(1):72.
4: Shah I, Malik MO, Khan MJ, Fatima S, Baxendale RH, Habib SH. Endostatin
Concentration In Plasma Of Healthy Human Volunteers. J Ayub Med Coll Abbottabad.
2017 Apr-Jun;29(2):200-206.
5: Carlsson AC, Wessman T, Larsson A, Leijonberg G, Tofik R, Ärnlöv J, Melander
O, Ruge T. Endostatin predicts mortality in patients with acute dyspnea – A
cohort study of patients seeking care in emergency departments. Clin Biochem.
2020 Jan;75:35-39.
6: Zheng MJ. Endostatin derivative angiogenesis inhibitors. Chin Med J (Engl).
2009 Aug 20;122(16):1947-51.
7: Sato Y. Endostatin as a Biomarker of Basement Membrane Degradation. J
Atheroscler Thromb. 2017 Oct 1;24(10):1014-1015.
8: Karamouzis MV, Moschos SJ. The use of endo_statin in the treatment of solid
tumors. Expert Opin Biol Ther. 2009 May;9(5):641-8.
9: Barroso MC, Boehme P, Kramer F, Mondritzki T, Koehler T, Gülker JE, Karoff M,
Dinh W. Endo_statin a Potential Biomarker for Heart Failure with Preserved
Ejection Fraction. Arq Bras Cardiol. 2017 Nov;109(5):448-456.
10: Yamaguchi Y, Feghali-Bostwick CA. Role of endostatin in fibroproliferative
disorders.-as a candidate for anti-fibrosis therapy-. Nihon Rinsho Meneki Gakkai
Kaishi. 2013;36(6):452-8.
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