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Molecular Depot Glutamate Dehydrogenase (Bovine Liver) B2010234
Glutamate Dehydrogenase (Bovine Liver) is a high purity (95%), high specific activity (19U/mg) freeze-dried powder of Glutamate Dehydrogenase (GLDH), a mitochondrial enzyme that catalyzes the oxidative deamination of glutamate into α-ketoglutarate. Custom bulk orders of this product are available upon request.
Glutamate Dehydrogenase (Bovine Liver)
Catalog number:B2010234
Lot number:Batch Dependent
Expiration Date:Batch dependent
Volume/Weight:20 mg
pH:na
Supplied as:Ready-to-use
Appearance:Lyophilized Powder
Applications:high purity (95%), high specific activity (19U/mg) freeze-dried powder of Glutamate Dehydrogenase (GLDH), a mitochondrial enzyme that catalyzes the oxidative deamination of glutamate into α-ketoglutarate.
Storage:-20°C
Keywords:GLDH, GDH, Glutamate Dehydrogenase
Grade:Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
References:
1: Smith HQ, Li C, Stanley CA, Smith TJ. Glutamate Dehydrogenase, a Complex
Enzyme at a Crucial Metabolic Branch Point. Neurochem Res. 2019
Jan;44(1):117-132.
2: Craze ML, El-Ansari R, Aleskandarany MA, Cheng KW, Alfarsi L, Masisi B, Diez-
Rodriguez M, Nolan CC, Ellis IO, Rakha EA, Green AR. Glutamate dehydrogenase
(GLUD1) expression in breast cancer. Breast Cancer Res Treat. 2019
Feb;174(1):79-91.
3: Jin Y, Li D, Lu S, Zhao H, Chen Z, Hou W, Ruan BH. Ebselen Reversibly
Inhibits Human Glutamate_Dehydrogenase at the Catalytic Site. Assay Drug Dev
Technol. 2018 Feb/Mar;16(2):115-122.
4: Li M, Li C, Allen A, Stanley CA, Smith TJ. Glutamate dehydrogenase:
structure, allosteric regulation, and role in insulin homeostasis. Neurochem
Res. 2014;39(3):433-45.
5: Plaitakis A, Zaganas I, Spanaki C. Deregulation of glutamate_dehydrogenase in
human neurologic disorders. J Neurosci Res. 2013 Aug;91(8):1007-17.
6: Spanaki C, Plaitakis A. The role of glutamate_dehydrogenase in mammalian
ammonia metabolism. Neurotox Res. 2012 Jan;21(1):117-27.
7: Hull J, Usmari Moraes M, Brookes E, Love S, Conway ME. Distribution of the
branched-chain α-ketoacid dehydrogenase complex E1α subunit and glutamate
dehydrogenase in the human brain and their role in neuro-metabolism. Neurochem
Int. 2018 Jan;112:49-58.
8: Shashidharan P, Plaitakis A. The discovery of human of GLUD2 glutamate
dehydrogenase and its implications for cell function in health and disease.
Neurochem Res. 2014;39(3):460-70.
9: Tomita T, Yin L, Nakamura S, Kosono S, Kuzuyama T, Nishiyama M. Crystal
structure of the 2-iminoglutarate-bound complex of glutamate_dehydrogenase from
Corynebacterium glutamicum. FEBS Lett. 2017 Jun;591(11):1611-1622.
10: Smith TJ, Stanley CA. Untangling the glutamate_dehydrogenase allosteric
nightmare. Trends Biochem Sci. 2008 Nov;33(11):557-64.
11: Nassar OM, Wong KY, Lynch GC, Smith TJ, Pettitt BM. Allosteric
discrimination at the NADH/ADP regulatory site of glutamate_dehydrogenase.
Protein Sci.2019 Dec;28(12):2080-2088.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
- Spectra Services shipping order number
- Date of invoice
- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
Non-Returnable Goods
Unfortunately, Spectra Services is unable to accept the following returns at this time:
- Products not in completely resalable condition (including products with damaged, missing, or defaced labeling or packaging
- Chemicals, reagents, diagnostics, sterile, or any controlled products (unless products do not meet specification
- Laboratory apparatus or instruments that have been used or are without the original packaging, labeling and operating manuals
- Refrigerated products or other perishables
- Products which are not inventoried by Spectra Services and are not able to be returned to the manufacturer
- Products purchased on a special order
- Products not purchased from Spectra Services
- Products with an expired shelf life or an expiration date too short for resale
- Discontinued products
Spectra Services reserves the right to review this policy on a case-by-case basis.
Pre-Owned Products
Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
All exchanges and returns require the completion of a Return Merchandise Authorization (RMA) form. Once completed, please return the merchandise immediately as the RMA number is only active for ten (10) days from the date of issuance.
Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
Spectra Services highly recommends that return packages be insured for full value and packaged securely to prevent shipping damage.
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Accidental damage during shipment can sometimes happen. When you take delivery of your freight, please inspect thoroughly for any visible damage to the outside of the shipping container before signing for it. If there are multiple pieces to the shipment, please account for all them. Should you find that any of the products are damaged or missing after receipt, contact us within three days to address the matter.
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