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Molecular Depot HDAC Assay Buffer 5X (Biotechnology Grade) B2010129
HDAC Assay Buffer 5X is a high quality research product used as optimized buffer for Histone Deacetylase Assays (HDAC). Custom bulk orders of this product are available upon request.
HDAC Assay Buffer 5X
Catalog number:B2010129
Lot number:Batch Dependent
Expiration Date:Batch dependent
Volume/Weight:10 mL
pH:8
Supplied as:5X Concentrate (Dilute 1:5 before use)
Appearance:Clear solution
Applications:optimized buffer for Histone Deacetylase Assays (HDAC).
Storage:−20°C
Keywords:HDAC buffer, hdac assay buffer, hdac activity assay buffer
Grade:Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
References:
1: Yoon S, Eom GH. HDAC and HDAC Inhibitor: From Cancer to Cardiovascular
Diseases. Chonnam Med J. 2016 Jan;52(1):1-11.
2: Hull EE, Montgomery MR, Leyva KJ. HDAC Inhibitors as Epigenetic Regulators of
the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases. Biomed
Res Int. 2016;2016:8797206.
3: Booth L, Roberts JL, Poklepovic A, Kirkwood J, Dent P. HDAC inhibitors
enhance the immunotherapy response of melanoma cells. Oncotarget. 2017 May
17;8(47):83155-83170.
4: Schobert R, Biersack B. Multimodal HDAC Inhibitors with Improved Anticancer
Activity. Curr Cancer Drug Targets. 2018;18(1):39-56.
5: Lyu X, Hu M, Peng J, Zhang X, Sanders YY. HDAC inhibitors as antifibrotic
drugs in cardiac and pulmonary fibrosis. Ther Adv Chronic Dis. 2019 Jul
18;10:2040622319862697.
6: Lu H, Bai L, Zhou Y, Lu Y, Jiang Z, Shi J. Recent Study of Dual HDAC/PARP
Inhibitor for the Treatment of Tumor. Curr Top Med Chem. 2019;19(12):1041-1050.
7: Hesham HM, Lasheen DS, Abouzid KAM. Chimeric HDAC inhibitors: Comprehensive
review on the HDAC-based strategies developed to combat cancer. Med Res Rev.
2018 Sep;38(6):2058-2109.
8: Li Y, Wang F, Chen X, Wang J, Zhao Y, Li Y, He B. Zinc-dependent Deacetylase
(HDAC) Inhibitors with Different Zinc Binding Groups. Curr Top Med Chem.
2019;19(3):223-241.
9: Kim T, Song S, Park Y, Kang S, Seo H. HDAC Inhibition by Valproic Acid
Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G
Transgenic Mice. Exp Neurobiol. 2019 Aug 31;28(4):504-515.
10: Amin SA, Adhikari N, Jha T. Is dual inhibition of metalloenzymes HDAC-8 and
MMP-2 a potential pharmacological target to combat hematological malignancies?
Pharmacol Res. 2017 Aug;122:8-19.
All returns must be authorized by Spectra Services in order to insure proper credit and must be requested within 30 days of purchase. All returns are subject to a minimum 15% restocking charge. For returns not due to error on behalf of Spectra Services, the customer is responsible for all transportation fees related to the returned product. To ensure proper credit, each product return must include the following information:
- Customer name and address
- Purchase order number
- Spectra Services shipping order number
- Date of invoice
- Item number of returned item(s)
- Spectra Services return authorization number (RMA)
- Reason for return
Non-Returnable Goods
Unfortunately, Spectra Services is unable to accept the following returns at this time:
- Products not in completely resalable condition (including products with damaged, missing, or defaced labeling or packaging
- Chemicals, reagents, diagnostics, sterile, or any controlled products (unless products do not meet specification
- Laboratory apparatus or instruments that have been used or are without the original packaging, labeling and operating manuals
- Refrigerated products or other perishables
- Products which are not inventoried by Spectra Services and are not able to be returned to the manufacturer
- Products purchased on a special order
- Products not purchased from Spectra Services
- Products with an expired shelf life or an expiration date too short for resale
- Discontinued products
Spectra Services reserves the right to review this policy on a case-by-case basis.
Pre-Owned Products
Upon receipt of the pre-owned product(s), the customer has one week to evaluate the product to ensure it meets their expectations. If for some reason the customer decides to return the product, they may do so at any point during those seven (7) days for a full refund. No restocking fee will be assessed, however, the customer is responsible for the return shipping costs. Full credit will be issued upon receipt and inspection of the item(s) to ensure equipment was returned in the same condition it was initially shipped out in.
Important Information
All exchanges and returns require the completion of a Return Merchandise Authorization (RMA) form. Once completed, please return the merchandise immediately as the RMA number is only active for ten (10) days from the date of issuance.
Charges associated with returning items are the responsibility of the customer unless the item(s) arrived defective, damaged, or incorrect.
Spectra Services highly recommends that return packages be insured for full value and packaged securely to prevent shipping damage.
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