The heart of the BIONOMIC SYSTEM© is the BC-100 CONTROLLER that regulates the temperature of a variety of "cells" designed to accept conventional substrate holder such as 60 and 35mm petri dishes, microscope slides, Dvorak chambers. Open and closed perfusion chambers are available. The flexibility of the system design allows special designed cells to be supplied for unique applications.

All Bionomic Cells may be adapted with a gas purging system that protects the specimen from the outside atmosphere.  Two gases such as N2 and CO2 may be accurately mixed in any ratio and gently purged over the substrate. The gas may be heated to reduce condensation when the Bionomic Cell and specimen are at sub-ambient temperature.

Bionomic Cells designed for low temperatures (less than 12° C) are water cooled to remove excess heat from the cooling elements.  A miniature, closed heat exchanger, the HEC-400 eliminates the need of using tap water and drains, preventing any possibility of water spills or floods and is recommended for use with the water cooled cells.